On this day, 182 years ago, on November 17, 1843 (September 26, 1843, the lunar calendar), Shanghai opened its port, and the Sino-foreign trade center gradually moved from Guangzhou to Shanghai. On November 17, 1843, Shanghai was opened as a port in accordance with the provisions of the Treaty of Nanjing and the Five-Port Trade Regulations. From then on, the Sino-foreign trade center gradually moved from Guangzhou to Shanghai. Foreign goods and foreign capital have entered the Yangtze River gateway, opened warehouses, set up docks, demarcated concessions, opened banks, etc. However, among them, the Mohai Press Printing House, which was founded by Madus when the port was opened, was the first enterprise opened by foreign capital in China. Madus is a missionary from the London Evangelist Society, England. The Mohai Press is a compilation and publishing institution he relocated his printing office in Batavia (now Jakarta) to China and named it in Chinese. It existed for about 20 years. The main business is printing Bibles and pamphlets used by the London Mission. After 1850, he also began to translate and publish a small number of scientific and technological books.