Thirty-seven years ago today, on November 23, 1988 (October 15, 1988 lunar calendar), Italy successfully cultivated AIDS test mice. On November 23, 1988, researchers at the San Matteo Hospital in Pavia, Italy, successfully cultivated HIV-infected test mice, providing a convenient test animal for the study of AIDS vaccines and therapeutic drugs, which is a major advance in AIDS research. The news was officially announced at the Milan Medical Symposium. The report said that the HIV-infected test mice were just bred by them. The method is to induce peritonitis first, and then inoculate infected cells. Using test mice for AIDS scientific research experiments is both economical and effective.