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On March 14, 1995, humans first obtained the genetic material of dinosaurs from fossilized dinosaur eggs
Thirty years ago today, on March 14, 1995 (February 14, 1995, the lunar calendar), humans first obtained dinosaur genetic material from dinosaur egg fossils. On March 14, 1995, a group of young scientists from the School of Life Sciences at Peking University recently successfully obtained dinosaur gene fragments from two special dinosaur egg fossils. This is the first time that humans have obtained dinosaur genetic material from dinosaur egg fossils. Scientists were pleasantly surprised that among dinosaur egg fossils, there were still bioactive substances from dinosaurs that had been extinct 65 million years ago. This discovery is of great significance for humans to understand dinosaurs and their living environment, the origin of species and the evolution of organisms. This Late Cretaceous C-type dinosaur egg fossil from Xixia County, Henan Province has an inner cavity with flocs in the cavity and is gray-brown. Zhang Yun, a professor at the School of Life Sciences at Peking University, took out a small amount of floc and found that it contained organic substances such as amino acids. Professor Chen Zhangliang and a group of young scholars in his laboratory used a complete set of molecular biology technologies and experimental equipment established in recent years, isotope labeling and PCR amplification technology to further confirm the existence of DNA in this dinosaur egg fossil, and successfully amplified a series of specific DNA fragments. Through DNA sequencing and computer comparison with the U.S. and European Community gene databases, multiple gene fragments were obtained, such as gene fragments homologous to 18SrDNA necessary for protein synthesis. The homology of 18SrDNA with amphibians, reptiles, birds, mammals and humans is 73% to 81%, but there is no homologous relationship with prokaryotes. This shows that the gene fragment is neither caused by human manipulation nor bacterial contamination. In addition, a gene related to cadherin was also obtained. Animal growth hormone receptor protein precursor gene, thyroid hormone receptor gene, zinc finger protein gene, and raw chicken histone gene and other fragments with high homology, these results were obtained through repeated experiments. These research results have opened up a new research field in palaeolecular biology. Some research results have been written into papers and published in the recently published Journal of Peking University.


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